Position immediately available to join a multidisciplinary research program exploring molecular pathophysiology of chronic pain and/or opioid-induced hyperalgesia. Projects include: 1) studying molecular signaling of neuronal TLR4 and RAGE receptors and their effects on voltage-dependent ion channels, and 2) the influence of neuronal chemokine signaling in neuropathic pain models. Experience with patch-clamp electrophysiology, calcium imaging, molecular biology, ion channel biochemistry preferred. Experimental approaches employed in the laboratory include electrophysiology, behavioral phenotyping, protein-protein interactions, whole-animal metabolic phenotyping, tissue culture, psychophysical studies of sensory-mediated behaviors, confocal microscopy, genetically-modified mouse models, transection and lesion analysis.
The appointment is for at least 2 years with the possibility to establish an independent program as a non-tenure track faculty member in the Department of Anesthesia, IU School of Medicine.
Minimum Qualifications:
Doctorate (MD and/or Ph.D. in medicine, biology, neuroscience, physiology, cell or molecular biology) is required.
Recent Ph.Ds. are preferred.
Applicant should demonstrate published expertise in one or more of the experimental approaches and exhibit strong long-term career ambition as a research scientist in the discipline of sensory physiology.
Excellent communication skills, both oral and written.
Send letter of interest, curriculum vitae, and three letters of reference to: Fletcher A. White, Ph.D., Vice Chair Research, Anesthesia, Indiana University School of Medicine (e-mail: fawhite@iupui.edu).
The White Lab is located in the Stark Neurosciences Research Institute (SNRI) which is housed in the new Research II Building on the Indiana University School of Medicine campus. A large proportion of the faculty that makes up the SNRI is interested in pain neurobiology. This unique research group includes investigations that range from quantifying changes in the activity of single ion channels to the physiological response of the whole animal (http://snri.iusm.iu.edu).
The list of primary investigators involved in pain research include:
Ted Cummins, Ph.D.
Jill C. Fehrenbacher, Ph.D.
Joyce Hurley, Ph.D.
Rajesh Khanna, Ph.D.
Grant Nicol, Ph.D.
Gerry Oxford, Ph.D.
Michael Vasko, Ph.D.
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