PostDoc in Molecular and Functional Neurobiology Group (m/f): Luxembourg, Luxembourg

　　The University of Luxembourg is a multilingual, international research University.

　　The University of Luxembourg has the following vacancy in the Luxembourg Centre for Systems Biomedicine (LCSB):

　　PostDoc in Molecular and Functional Neurobiology Group (m/f)

　　Ref.: R-AGR-0242-10-C ( Model IPD)

　　Fixed-term contract 24 months,

　　Full-time position (40h/week)

　　Start date: as soon as possible

　　Employee status

　　Research project:

　　The postdoctoral fellow will be involved in the ATTRACT project entitled: “Modelling idiopathic Parkinson’s disease-associated somatic variation in dopaminergic neurons”. The aim of this FNR-funded research we aim to investigate the involvement of the mitochondrial genome in the pathogenesis of Parkinson's disease using stem cell-derived cellular models and postmortem brain tissue.

　　Your tasks/mission:

　　Generation/maintenance of induced pluripotent stem cells and subsequent differentiation into dopaminergic neurons

　　Design and application of experiments to assess the impact of mtDNA defects on mitochondrial and neuronal function

　　Application of single-cell analysis approaches to post-mortem tissue sections (histology, quantitative immunofluorescence, laser capture micro dissection)

　　Student supervision

　　For further information, please contact Prof. A. Grünewald at anne.gruenewald@uni.lu

　　Your profile:

　　PhD in Cellular Biology, Neuroscience, or related discipline

　　Strong interest in interdisciplinary research and cellular models of neurodegeneration

　　Track record in research and laboratory work as documented by publications in internationally acknowledged journals

　　Profound knowledge of molecular genetics, biochemistry and cell biology

　　Expertise with inducible pluripotent stem cell models

　　Experience with histology, immunofluorescence analysis and laser capture microdissection

　　Previous experience with CRISPR/Cas9 gene editing desirable

　　Excellent communication, team-working and interpersonal skills

　　Previous experience as supervisor of students

　　Enthusiasm and great commitment to research

　　Very good command of the English language

　　We offer:

　　Fully funded position with the possibility of renewal for up to 5 years depending on availability of funding

　　Exciting international research environment

　　Opportunity to participate in the development of the LCSB

　　Travel opportunities to national and international meetings as well as participation in specialized trainings

　　The University of Luxembourg offers competitive compensation and is an equal opportunity employer

　　Applications (in English) should contain the following documents:*

　　Detailed Curriculum Vitae including a list of publications

　　Cover letter mentioning the reference number

　　Description of past research experience and future interests

　　Copies of diploma and transcripts

　　Name and addresses of three referees

　　Please apply online until the 15th of October 2018

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