招聘簡介：

　　紐約大學醫(yī)學院的Holger Knaut團隊尋求具有細胞生物學、熒光顯微鏡或生物物理學經(jīng)驗的高動機、注重細節(jié)和熱情的博士或醫(yī)學博士畢業(yè)生，以探索與使用定量imagi的活動物在形態(tài)發(fā)生過程中調(diào)節(jié)細胞行為相關(guān)的項目。遺傳學和計算建模。

　　我們小組的目標是破譯形態(tài)發(fā)生過程中動態(tài)細胞行為的物理、分子和細胞原理。我們希望揭示這些原理將提供對正常細胞動力學如何促進發(fā)育和體內(nèi)平衡以及為什么擾動會導致缺陷和疾病的理解。

　　我們實驗室用來理解動態(tài)細胞行為的當前模型是神經(jīng)元聚集成團（Lewellis等人細胞生物學雜志。2013），《感覺器官的組織運動》（Venkiteswaran G等人細胞。2013年，Wang J等人發(fā)育細胞。以及斑馬魚冠狀動脈網(wǎng)絡(luò)的形成（Nagelberg D等人當代生物學。2015）。為了研究這些過程，我們通常與其他實驗室合作，使用經(jīng)典遺傳學、基因組工程、先進的熒光顯微鏡和計算模型。

　　英文原文：

　　The group of Holger Knaut at NYU School of Medicine seeks highly motivated, detail orientated, and passionate Ph.D. or M.D. graduates with experience in cell biology, fluorescence microscopy or biophysics to explore projects related to the regulation of cellular behaviors during morphogenesis in the context of live animals using quantitative imaging, genetics and computational modeling.

　　The goal of our group is to decipher the physical, molecular and cellular principles underlying dynamic cell behaviors during morphogenesis. We hope that uncovering these principles will provide an understanding of how normal cell dynamics contributes to development and homeostasis and why perturbations cause defects and disease.

　　Current models our lab uses to understand dynamic cell behavior are the assembly of neurons into clusters (Lewellis S et al. Journal of Cell Biology. 2013), the tissue movement of sensory organs (Venkiteswaran G et al. Cell. 2013, Wang J et al. Developmental Cell. 2018) and the formation of the coronary artery network in zebrafish (Nagelberg D et al. Current Biology. 2015). To interrogate these processes we use classical genetics, genome engineering, advanced fluorescence microscopy and computational modeling, often in collaboration with other laboratories.

　　Our group is located in the Skirball Institute of the NYU School of Medicine in midtown Manhattan (New York City). The Skirball Institute is a premier institution for biomedical research. The institute focuses boldly on basic research. It also provides excellent core facilities and a supportive environment for interactions between its labs and the clinical disciplines at NYU Langone Medical Center. With a strong awareness that most medical breakthroughs originate in basic research, the medical center has allocated considerable resources in developing a state-of-the-art, modern, interdisciplinary research unit right in the center of the medical school environment.

　　Candidates should have a recent MD, PhD or MD/PhD degree and a strong background in cell biology, fluorescent microscopy or biophysics. Although not essential, candidates with experience in the use of animal models are encouraged to apply. Please send a cover letter explaining relevant work experience and interests, a CV, and the contact information of three references to Holger Knaut at holger.knaut@med.nyu.edu.

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